Mihajlovic has a poor record against his former club, managing only one win for Catania back in 2009-10. Since then he’s faced Lazio six times, emerging with just a single point.
Injuries rule out Mario Balotelli, Jeremy Menez and Ignazio Abate, but Mbaye Niang is on the bench for the first time since fracturing his foot in early August.
Lazio bench: Berisha, Guerrieri, Braafheid, Radu, Hoedt, Konko, 在线外围投注Cataldi, Mauri, Morrison, Onanzi, Djordjevic, Kishna, Matri
Cerci’s improving form sees him maintain his spot in the trident attack with Bacca and Jack Bonaventura, but Nigel De Jong is left out of midfield.
Stefano Pioli must do without injured Stefan de Vrij, who will be out for around four months after agreeing to knee surgery, Marco Parolo and Keita Balde Diao.
Milan again pick 16-year-old goalkeeper Gianluigi Donnarumma, who midweek kept their first clean sheet of the campaign.
Lazio: Marchetti; Basta, Mauricio, Gentiletti, Lulic; Onanzi, Biglia; Candreva, Milinkovic-Savic, Felipe Anderson; Klose
It kicks off in Rome at 19.45 GMT,
They are also unbeaten here against Milan in five meetings, including three victories.
Milan: Donnarumma; De Sciglio, Alex, Romagnoli, Antonelli; Kucka, Montolivo, Bertolacci; Cerci, Bacca, Bonaventura
If Lazio instead maintain their perfect home record so far this season in all competition, they’ll climb to fifth, just one point behind Napoli.
Milan bench: Abbiati, Diego Lopez, Calabria, Zapata, Mexes, Poli, De Jong, Jose Mauri, Suso, Honda, Niang, Luiz Adriano
There’s plenty at stake, because a win would propel Sinisa Mihajlovic’s澳门外围投注 men into sixth position, ahead of the Aquile.
Veteran hitman Klose returns to lead the attack, supported by Felipe Anderson, Sergej Milinkovic-Savic and Antonio Candreva.
Lazio have a 100 per cent record at the Olimpico in all competition this season.
Lazio look to Miroslav Klose and Felipe Anderson against Milan’s Carlos Bacca 皇冠外围投注and Alessio Cerci in this head-to-head for fifth place.